18 Influence of some aromatic amino acids on the swelling behavior of acrylamide/maleic acid hydrogel

Author(s): Oztop, HN; Saraydin, D; Karadag, E; Caldiran, Y; Guven, O

Title: Influence of some aromatic amino acids on the swelling behavior of acrylamide/maleic acid hydrogel

Source: POLYMER BULLETIN, 40 (4-5): 575-581 APR-MAY 1998

Language: English

Document Type: Article

Keywords Plus: BOVINE SERUM-ALBUMIN; ADSORPTION; BIOCOMPATIBILITY

Abstract: Influence of some aromatic amino acids (histidine, phenylalanine and tryptophan) on the swelling behavior of acrylamide/maleic acid hydrogel (AAm/MA) prepared by gamma-radiation was investigated. Swelling tests of AAm/MA hydrogel were made in buffer solutions and amino acid solutions at various pH at 37 degrees C. The pH values are ionization of alpha-carboxyl groups (pK(1)'), alpha-amino groups (pK(2)') and, isoelectric points (pI) of amino acids. The swelling of AAm/MA hydrogel increased when pH values of solutions were increased. The value of equilibrium swelling of AAm/MA hydrogel was 1035% at pH 10 buffer, while it was 880% at pH 2 buffer. The values of equilibrium swelling of AAm/MA hydrogel in phenylalanine, tryptophan and histidine solutions varied among 1130-1245% at pH 10, while they were among 790-975% at pH 2. The rate constant of swelling, diffusional exponent, network parameter and, diffusion and intrinsic diffusion coefficient were calculated by swelling kinetics. Diffusion of the penetrants into the hydrogel was found to be non-Fickian character. The diffusion coefficients of the hydrogel varied between 3.33x10(-6) -7.71x10(6) cm (2)s(-1), while the intrinsic diffusion coefficients varied between 4.03x10(-6)-8.48x10(-6) cm (2)s(-1).

Addresses: Cumhuriyet Univ, Dept Chem, TR-58140 Sivas, Turkey; Adnan Menderes Univ, Dept Chem, TR-09010 Aydin, Turkey; Hacettepe Univ, Dept Chem, TR-06532 Ankara, Turkey

Reprint Address: Saraydin, D, Cumhuriyet Univ, Dept Chem, TR-58140 Sivas, Turkey.

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Cited Reference Count: 15

Times Cited: 10

Publisher: SPRINGER VERLAG

Publisher Address: 175 FIFTH AVE, NEW YORK, NY 10010 USA

ISSN: 0170-0839

29-char Source Abbrev.: POLYM BULL

ISO Source Abbrev.: Polym. Bull.

Source Item Page Count: 7

Subject Category: POLYMER SCIENCE

ISI Document Delivery No.: ZL808