Record 32 Nicotine-selective radiation-induced poly(acrylamide/maleic acid) hydrogels

Author(s): Saraydin, D; Karadag, E; Caldiran, Y; Guven, O

Title: Nicotine-selective radiation-induced poly(acrylamide/maleic acid) hydrogels

Source: RADIATION PHYSICS AND CHEMISTRY, 60 (3): 203-210 FEB 2001

Language: English

Document Type: Article

Author Keywords: hydrogel; poly(acrylamide/maleic acid); nicotine; sorption; interaction

Keywords Plus: BOVINE SERUM-ALBUMIN; CATIONIC DYES; AQUEOUS-SOLUTIONS; ADSORPTION; BIOCOMPATIBILITY; PARAMETERS; BEHAVIORS

Abstract: Nicotine-selective poly(acrylamide/maleic acid) (AAm/MA) hydrogels prepared by gamma -irradiation were used in experiments on swelling, diffusion, and interactions of the pharmaceuticals nicotine, nicotinic acid, nicotinamide. and nikethamide. For AAm/MA hydrogel containing 60 mg maleic acid and irradiated at 5.2 kGy, the studies indicated that swelling increased in the following order; nicotine > nicotinamide > nikethamide > nicotinic acid > water. Diffusions of water and the pharmaceuticals within the hydrogels were found to be non-Fickian in character. AAm/MA hydrogel sorbed only nicotine and did not sorb nicotinamide, nikethamide and nicotinic acid in the binding experiments. S-type adsorption in Giles's classification system was observed. Some binding and thermodynamic parameters for AAm/MA hydrogel-nicotine system were calculated using the Scatchard method. The values of adsorption heat and free energy of this system were found to be negative whereas adsorption entropy was found to be positive. (C) 2001 Elsevier Science.

Addresses: Cumhuriyet Univ, Dept Chem, TR-58140 Sivas, Turkey; Adnan Menderes Univ, Dept Chem, TR-09010 Aydin, Turkey; Hacettepe Univ, Dept Chem, TR-06532 Ankara, Turkey

Reprint Address: Saraydin, D, Cumhuriyet Univ, Dept Chem, TR-58140 Sivas, Turkey.

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Cited Reference Count: 27

Times Cited: 9

Publisher: PERGAMON-ELSEVIER SCIENCE LTD

Publisher Address: THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND

ISSN: 0969-806X

29-char Source Abbrev.: RADIAT PHYS CHEM

ISO Source Abbrev.: Radiat. Phys. Chem.

Source Item Page Count: 8

Subject Category: CHEMISTRY, PHYSICAL; PHYSICS, ATOMIC, MOLECULAR & CHEMICAL; NUCLEAR SCIENCE & TECHNOLOGY

ISI Document Delivery No.: 409MG