38 In vitro dynamic swelling behaviors of radiation synthesized polyacrylamide with crosslinkers in the simulated physiological body fluids

Author(s): Saraydin, D; Isikver, Y; Karadag, E; Sahiner, N; Guven, O

Title: In vitro dynamic swelling behaviors of radiation synthesized polyacrylamide with crosslinkers in the simulated physiological body fluids

Source: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS, 187 (3): 340-344 MAR 2002

Language: English

Document Type: Article

Author Keywords: acrylamide; hydrogel; ionizing radiation; simulated body fluids; biomaterials

Keywords Plus: MALEIC-ACID HYDROGELS; BOVINE SERUM-ALBUMIN; AMINO-ACIDS; ADSORPTION

Abstract: Acrylamide hydrogels, containing different amounts and types of crosslinkers, were synthesized via gamma-irradiation technique. Their swellings in simulated body fluids, such as physiological saline (0.89% NaCl) isoosmotic phosphate buffer at pH 7.4, gastric fluid at pH 1.1 (glycine-HCl), protein (aqueous solution of bovine serum albumin), urine (aqueous solution of urea), glucose and distilled water, were studied. Equilibrium swellings of the hydrogels were changed in the range 27-85 depending upon the fluids, type and amount of crosslinkers. The diffusion exponents were found over half for all hydrogels. (C) 2002 Elsevier Science B.V. All rights reserved.

Addresses: Cumhuriyet Univ, Dept Chem, Hydrogel Res Lab, TR-58140 Sivas, Turkey; Adnan Menderes Univ, Dept Chem, TR-09010 Aydin, Turkey; Hacettepe Univ, Dept Chem, TR-06532 Ankara, Turkey

Reprint Address: Saraydin, D, Cumhuriyet Univ, Dept Chem, Hydrogel Res Lab, TR-58140 Sivas, Turkey.

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Cited Reference Count: 20

Times Cited: 0

Publisher: ELSEVIER SCIENCE BV

Publisher Address: PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS

ISSN: 0168-583X

29-char Source Abbrev.: NUCL INSTRUM METH PHYS RES B

ISO Source Abbrev.: Nucl. Instrum. Methods Phys. Res. Sect. B-Beam Interact. Mater. Atoms

Source Item Page Count: 5

Subject Category: PHYSICS, ATOMIC, MOLECULAR & CHEMICAL; PHYSICS, NUCLEAR; INSTRUMENTS & INSTRUMENTATION; NUCLEAR SCIENCE & TECHNOLOGY

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